The FY17 Defense Appropriations Act provides $8 million (M) to the Department of Defense MBRP to support a broad research portfolio in the treatment of burns and the trauma associated with burn injuries sustained during combat or combat-related activities. Applications to the FY17 MBRP are being solicited by the U.S. Army Medical Research Acquisition Activity. The managing agent for the anticipated Program Announcements/Funding Opportunities is the Congressionally Directed Medical Research Programs (CDMRP).
FY17 MBRP Program Announcements and General Application Instructions for the following award mechanisms are posted on Grants.gov.
To be considered for funding, each application for the FY17 MBRP Clinical Trial Award must address the following Topic Area:
Clinical studies that involve the prevention, treatment, and mitigation of debilitating burn scars (e.g., dressing topics, biologics, cell-based therapies, mechanical, photonics, etc.) to improve functional outcomes and/or assess clinical efficacy and safety of different treatment modalities.
Clinical Trial Award – Preproposal due August 3, 2017
- · Independent investigators at all academic levels (or equivalent) are eligible to submit applications.
- Research Level 1: This level will support early-stage clinical trials (i.e., proof-of-concept, pilot, first-in-human, or Phase 0) to address the Topic Area.
- Research Level 2: This level will support Phase I and/or Phase II multi-center clinical trials that address the Topic Area and assess the clinical efficacy and safety of different treatment modalities.
- Funding must support a clinical trial and may not be used for preclinical studies.
- · Inclusion of preliminary data relevant to the proposed clinical trial is required.
- · Investigational New Drug or Investigational Device Exemption applications, if needed, should be submitted to the Food and Drug Administration within 6 months of the award date.
· For Research Level 1
· Maximum funding of $1.75M for total costs (direct and indirect).
· Maximum period of performance is 4 years.
· Maximum funding of $3.5M for total costs (direct and indirect).
- · Maximum period of performance is 4 years.
A pre-application is required and must be submitted through the electronic Biomedical Research Application Portal (eBRAP) at https://eBRAP.org prior to the pre-application deadline. All applications must conform to the final Program Announcements and General Application Instructions available for electronic downloading from the Grants.gov website. The application package containing the required forms for each award mechanism will also be found on Grants.gov. A listing of all CDMRP funding opportunities can be obtained on the Grants.gov website by performing a basic search using CFDA Number 12.420.
Applications must be submitted through the Federal Government’s single-entry portal, Grants.gov. For email notification when Program Announcements are released, subscribe to program-specific news and updates under “Email Subscriptions” on the eBRAP homepage at https://eBRAP.org. For more information about the MBRP or other CDMRP-administered programs, please visit the CDMRP website (http://cdmrp.army.mil).
Point of Contact:
CDMRP Help Desk